Correspondence on "New EULAR/ACR 2019 SLE classification criteria: defining ominosity in SLE"

Abstract

Sparks et al are to be congratulated on an important and timely study. They found that the use of JAKi was associated with worse outcome of COVID-19 infection, and they interpret this as a harmful effect of the treatment in that particular setting. Butthis question deserves further consideration. Assuming that the observation is correct, what could the mechanism be? As the authors correctly point out, some JAKi’s did show benefits for patients with severe COVID-19 infection.2 3 We, therefore,propose an alternative explanation of the observed data...